Lymphocyte receptors for concanavalin A in Hodgkin disease
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چکیده
منابع مشابه
Lymphocyte receptors for concanavalin A in Hodgkin disease.
The number of lymphocytes with mobile receptors for concanavalin A (Con A) on their surface membrane (forming visible caps after the addition of fluorescein-conjugated Con A) was determined in the peripheral blood of 53 patients with Hodgkin disease. Of 29 individuals studied prior to treatment, the level of capped cells was found to be below the normal range in 9 of 13 in stages I and IIA, 6 o...
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The effect of concanavalin A (Con A) on the capping of mouse lymphocyte surface immunoglobulin (surface Ig), cross-linked by rabbit anti-mouse Ig antibody, and on the capping of mouse thymocyte theta antigen, cross-linked by anti-theta alloantibody and rabbit anti-mouse Ig antibody, has been studied by immunofluorescence, using fluorescein conjugated Con A and rhodamine-conjugated anti-mouse Ig...
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SUMMARY Hodgkin's disease has been known to medical practitioners for more than three centuries. The clinical and pathologic description of the disease published by Thomas. Hodgkin first in 183 2 when reported seven cases th-at he considered a new clinical entity. The incident, clinical feature, histologic, procedure of evaluation and staging of Hodgkin's disease are presented briefly. Part...
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Chemical derivatization of tetrameric concanavalin A (Con A) with succinic anhydride or acetic anhydride converts the protein to a dimeric molecule without altering its carbohydrate-binding specificity. At low concentrations, the dose-response curves for the mitogenic stimulation of mouse spleen cells by native Con A and succinyl-Con A are similar. Above lectin concentrations of 10 ug/ml, howev...
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ژورنال
عنوان ژورنال: Blood
سال: 1978
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v51.3.439.439